It is also known as leucoderma or achromoderma. Most patients are reassured of the benign nature of the condition and no treatment is recommended. Avoiding direct sunlight and using high spf sunscreen can help protect from the detrimental effects of sunrays. 2013 May 8. 2011 Jul. Berry J. Idiopathic guttate hypomelanosis is a common acquired skin condition characterized by multiple discrete, round, porcelain-white macules on the extensor aspects of the extremities in the elderly population. Pityriasis versicolor CME. Your age, race and family history will also be considered by your healthcare professional for an assessment of your skin condition. This includes areas like the arms and legs. Contact leukoderma is initially localised to the site of contact, with subsequent multiple small confetti-like white spots spreading beyond the known contact area. 5-Fluorouracil in Dermatology: The Diverse Uses Beyond Malignant and Premalignant Skin Disease. Genetics Home Reference; Oculocutaneous Albinism; Accessed 5 th June 2020. An African-American patient with idiopathic guttate hypomelanosis on her leg. Leukoderma may recover slowly if the cause can be avoided, such as cessation of a drug or chemical exposure, or treated such as inflammatory dermatoses. MMP is a procedure done with tattoo devices using medication in place of ink. But, the uneven skin coloration may be a reason for psychological stress in some people, who therefore opt for different treatment strategies to get a more even complexion. Disclaimer - the author PCDS cannot accept responsibility for any misleading or incorrect statements, and the management of individual patients remains the direct responsibility of the individual doctor. Pigmentation tends to be persistent but can fade slowly after pregnancy or after discontinuing oral contraception. Hypopigmentation disorders may be congenital or acquired, diffuse (generalized) or localized, and may occur in isolation or be associated with a wide range of congenital or acquired disorders [ 2-4 ]. Idiopathic Guttate Hypomelanosis (IGH) is a leukoderma of unknown cause (idiopathic). Guttate leukoderma can be an early sign of Darier disease seen particularly in skin of colour. Hypopigmentation is mostly harmless and most forms of skin discolorations go away by themselves over a certain period of time. 2014 Jan. 5 (1):14-8. The appearance is said to be like spaghetti and meatballs. Localised hypopigmentation: clarification of a diagnostic conundrum. conditions. [1] Loss of melanin in a particular area of your skin results in patches that are lighter or whiter than your basal skin tone. [QxMD MEDLINE Link]. Vitiligo is an acquired disorder of melanocytes characterized by complete loss of pigment within the skin to yield depigmented macules and patches. Gordon JR, Reed KE, Sebastian KR, Ahmed AM. Shin J, Kim M, Park SH, Oh SH. 80 (2):141-4. Ravikiran SP, Sacchidanand S, Leelavathy B. Epub 2021 Jul 25. Pustules (small pus-filled lesions) / boils Ask your doctor about using topical steroids. Go to Top of Page Excimer light treatment will be performed on patients randomized to receive treatment on the right leg and left leg will be untreated control It appears as multiple round or oval macules of depigmentation or hypopigmentation, mostly over the upper or lower extremities. Controlled exposure to sunlight may help in production of melanin, which evens out the skin tone. Last but not the least the uneven skin coloration and white patches affects the looks of a person. ownership. Please enable it to take advantage of the complete set of features! 2019;20(22):5731. doi:10.3390/ijms20225731. Drug (or chemical) related Accessed 12 th February 2021 Available: athic-guttate-hypomelanosis 34. Pigment Cell Melanoma Res. Although often called tinea versicolor this name is incorrect, as pityriasis versicolor is not due to dermatophyte fungi. 28 (3):271-275. Study record managers: refer to the Data Element Definitions if submitting registration or results information. Women are more commonly affected. The etiology is poorly understood in black people. [QxMD MEDLINE Link]. Seborrhoeic eczema 29. Leukoderma, Author: Vanessa Ngan, Staff Writer, 2003; Updated: Katrina Tan, Medical Student, Monash University, Melbourne, Australia; Dr Martin Keefe, Dermatologist, Christchurch, New Zealand. Referral pathways 2. WebIdiopathic guttate hypomelanosis is a common condition characterised by the presence of numerous, small, white macules found predominantly on the shins and forearms. Progress in preventing idiopathic guttate hypomelanosis can be made by educating young women not to tan their legs. Vitiligo affects approximately 1% of the population and both genders equally. People with different skin types develop idiopathic guttate hypomelanosis. Women are more commonly affected. Chemical-induced vitiligo. 2015;42(2):21518. Dermoscopy can be helpful in the diagnosis of some forms of leukoderma. J Dermatolog Treat. This might take upto a year to show any visible results. Vitiligo is an acquired disorder of melanocytes and is characterized by complete loss of pigment. Skip areas of retained melanin can help histologically differentiate this condition from other disorders of pigmentation. [QxMD MEDLINE Link]. Our studies have shown that significantly fewer dopa-positive melanocytes are in the white macules of idiopathic guttate hypomelanosis than in normal skin. Leukoderma is the visible result of loss of epidermal melanin. [QxMD MEDLINE Link]. Also known as diffused hypopigmentation, generalised hypopigmentation affects the entire body. C. You can try a hydroquinone containing gel for evening out skin discoloration. Acne vulgaris 5. 27(4):460-4. Int J Dermatol. Acta Derm Venereol. 8600 Rockville Pike 1999 Jul. Unwell with eg fever / malaise These spots are small, but they can appear unsightly and unattractive. Please refer to notes on image rights at bottom of the page with regards to individual image Bleaching agents with hydroquinone (a hydroxyphenolic compound that inhibits the conversion of dopa to melanin), in concentrations of 2% to 4%, can help to minimize (lighten) the pigmentation. The https:// ensures that you are connecting to the Treatment is usually not required as the marks are completely harmless. WebIdiopathic guttate hypomelanosis (IGH) manifests as small white spots on skin that receives high amounts of sun exposure. Aggravated by cold or heat By accessing or using this website, you agree to abide by the Medical Disclaimer, Terms of Service, Privacy Policy, and Affiliate Disclosure. Ears I shall book again and already shared with colleagues eCollection 2022 Sep-Oct. Affected patients have asymptomatic brown patches symmetrically on the upper lips, cheeks, forehead, and chin. Cryotherapy and dermabrasion may have some benefit. American Society of Dermatologic Surgeons. Arch Dermatol. A few common causes of hypopigmentation include: This form of hypopigmentation is followed by a previous skin problem, such as the following: (i) Inflammatory skin diseases like atopic dermatitis, lichen striatus, etc. Boils and folliculitis (including hid 8. Perioral dermatitis 21. Alopecia (hair loss) - an overview 6. [4], There may be a genetic component to IGH, as families of IGH patients have a greater incidence of IGH when compared to controls. [QxMD MEDLINE Link]. Most patients are pregnant women in whom the darkening is considered physiologic, although nonpregnant women taking oral contraceptives or estrogens can also develop melasma. doi:10.1016/j.jdcr.2017.09.021. Ultrastructural study. Dermatoscopic examination may aid in diagnosis. health professionals, and the general public on skin Dermatol Surg. Hypopigmentation may be localised or generalised. Dopa Idiopathic guttate hypomelanosis is most common in countries with fair-skinned populations having a high degree of sun exposure. I'm happy to hear that it has a name and that it won't spread to my face. The doctor may further ask you to go for a skin biopsy if leprosy, sarcoidosis or other malignancies are suspected. Pityriasis alba (large patches on face and upper arms), Pityriasis rosea (short history and rapid onset), Topical/oral azoles including clotrimazole, miconazole, econazole and ketoconazole in various, Pityrosporum folliculitis (superficial acne-like. Int J Mol Sci. Pityriasis versicolor fluoresces blue-green on examination using a Wood lamp (long wavelength UVA1). Nutritional deficiency of vitamin B12, copper or iron. Brown patches Listing a study does not mean it has been evaluated by the U.S. Federal Government. B. Histologically, a decrease in the number of melanocytes is found and women, especially over 40 years of age, represent the majority of cases. On the nature of idiopathic guttate hypomelanosis. Last reviewed: June 2017. 79(4):305-10. "Incontinentia pigmenti achromians (Ito)". Lichen sclerosus In very rare cases hypopigmentation may be associated with certain forms of cancers. Drug rashes 10. Child abuse / domestic violence Pityriasis versicolor Treatment of your hypopigmentation will depend on the underlying cause therefore a correct diagnosis of your condition is essentially the first step towards its treatment. Pityriasis versicolor presents as asymptomatic flaky patches on the trunk, neck, and/or arms, which persist for months or years. REMEDIES Activated Unauthorized use of these marks is strictly prohibited. Idiopathic guttate hypomelanosis progresses with increasing sun exposure and, to a lesser degree, with age. Note that this may not provide an exact translation in all languages, Home Recommend washing affected areas with an anti-dandruff shampoo twice weekly to reduce the chance of relapse. Thus, the face, neck, hands and arms are most often affected. But in rare cases hypopigmentation may be associated with skin cancers especially in patients with albinism. This article contains scientific references. WebA: Your condition has a long name with lots of syllables: idiopathic guttate hypomelanosis. How Long Does Hypopigmentation Resulting As A Side Effect Of Treatment Last? Pigmentary disorders typically indicate an increased amount of melanin, leading to darker color of the skin, called hypermelanosis or hyperpigmentation (Box 1). 2021 Feb 17;23(1-2):8-15. doi: 10.1080/14764172.2021.1957116. Standard safety vitiligo protocols were followed; for instance, if burning occurred, fluence was adjusted appropriately. Arms and legs Indian Dermatol Online J. Because there is no standard therapy for this condition, numerous medical and surgical treatments including intralesional corticosteroids, topical retinoids, topical calcineurin inhibitors, phenol peeling, cryotherapy, superficial dermabrasion, skin grafting, and ablative and non-ablative lasers have been tested with mixed results. Certain forms of hypopigmentation such as vitiligo, albinism etc. For fungal or bacterial infections, appropriate antifungal or antibiotic medications will be prescribed by your doctor. William D James, MD Paul R Gross Professor of Dermatology, Vice-Chairman, Residency Program Director, Department of Dermatology, University of Pennsylvania School of Medicine Thank you for your feedback on this article.
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